ACMSD antibody
Cat.#: S2791
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q8TDX5
Mol Weight: 38.04kDa
Size: 100ug
Description
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM]
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
Species Reactivity
Human
Other species have not been tested
Products Data
Sample (30ug of whole cell lysate)
A: Molt-4
B: Raji
10% SDS PAGE
diluted at 1:1000
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 105 and 307 of Human ACMSD
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
ACMSD antibody, - antibody, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody, Picolinate carboxylase antibody
