ALDH5A1 antibody
Cat.#: S2075
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P51649
Mol Weight: 58.66kDa
Size: 100ug
Description
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
Species Reactivity
Human
Other species have not been tested
Products Data
Sample (30ug of whole cell lysate)
A: A431
7.5% SDS PAGE
diluted at 1:1000
Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 85 and 334 of human ALDH5A1
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
ALDH5A1 antibody, SSADH antibody, SSDH antibody, Succinate-semialdehyde dehydrogenase, mitochondrial antibody, Aldehyde dehydrogenase family 5 member A1 antibody, NAD(+)-dependent succinic semialdehyde dehydrogenase antibody
