| 货号 | CAS号 |
|---|---|
| M127026-10mg | 86347-14-0 |
| M127026-100mg | 86347-14-0 |
| M127026-5mg | 86347-14-0 |
| M127026-1g | 86347-14-0 |
| 溶解性 | DMSO |
| 存贮条件 | 储存温度2-8℃ |
| 产品介绍 | Medetomidine(Domtor)是α2肾上腺素受体激动剂，对α2和α1肾上腺素受体的Ki分别为1.08 nM和1750 nM。 |
| 生化机理 |
Medetomidine is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). Medetomidine displays greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Medetomidine inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. |
| 别名 | 美托咪定;美托嘧啶;Domtor;dl-Medetomidine; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole |
