| 应用 |
A Wnt inhibitor. |
| 产品介绍 |
KY02111抑制Wnt信号，促进hPSCs分化为心肌细胞，可能对APC和GSK3β的下游起作用。 |
| 备注 |
KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β. |
| 生化机理 |
KY02111 promotes differentiation of human pluripotent stem cells (hPSCs) to cardiomyocytes by inhibiting WNT signaling in hPSCs in a manner that is distinct from that of previously studied WNT inhibitors. The substantial (98%) differentiation of hPSCs to cardiomyocytes with KY02111 is achieved in xeno-free and cytokine-free conditions. |
| 别名 |
N-(6-氯-2-苯并噻唑基)-3,4-二甲氧基苯丙酰胺;KY 02111; KY-02111;KY 02111; KY-02111;
N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide |
