FK-506,>98%

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M.Wt: 804.02


Formula: C44H69NO12





Solubility: Soluble in DMSO, Ethanol





Purity: >98 %





CAS No: [104987-11-3]















































Cat No

Size

Price($)


BC029-050

50mg

125


BC029-100

100mg

230


BC029-500

500mg

540










 














 

















Biological Activity:

FK-506 is a potent immunosuppressant and in vitro T cell proliferation blocker. It has been shown to disrupt calcineurin (also known as CaN or phosphatase 2B)-mediated signal transduction in T lymphocytes. The compound interacts with its FK506-binding protein-12 (FKBP12). The resulting complex, in turn, interferes with calcineurin substrate interaction.


Synonym

Tacrolimus

Fujimycin

Prograf





Store at -20oC, Desiccate




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