BML-SA637-0200 200 µl
BML-SA637-0050 50 µl
CaSR is a member of subfamily C of the G-protein-coupled receptor superfamily. As its primary role, CaSR is a key player in calcium homeostasis and is expressed in tissues involved in calcium metabolism, such as parathyroid cells and kidney. CaSR activation is followed by a rapid, transient increase in the cytosolic calcium concentration, resulting from mobilization of calcium from thapsigargin-sensitive intracellular stores, as well as an increased calcium influx through voltage-insensitive calcium channels located at the cell membrane.
CaSR regulates cellular processes such as proliferation, apoptosis, and differentiation under both normal and pathologic conditions.
Product Specification
Alternative Name: CaSR
Immunogen: Synthetic peptide corresponding to aa 216-229 of human CaSR (calcium sensing receptor).
Source/Host: From rabbit.
Specificity: Recognizes rat, mouse and human CaSR.
Application: Flow Cytometry
Immunocytochemistry
Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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