BML-SL100-0025 25 mg
BML-SL100-0005 5 mg
N-Acetylsphingosine is a biologically active, cell-permeable ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A4, activates MAP kinase and SAP kinase and induces PKCδ and ε translocation. Physiological levels of C2 ceramide, produced by the action of a PAF:sphingosine CoA-independent transacetylase, have been detected in HL-60 cells.
Product Specification
Alternative Name: N-Acetyl-D-erythro-sphingosine
Formula: C20H39NO3
MW: 341.5
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 3102-57-6
Solubility: Soluble in 100% ethanol (>25mg/ml) or DMSO (>50mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
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