BML-T104-0250 250 mg
BML-T104-0025 25 mg
BML-T104-0005 5 mg
Antitumor agent. Stabilizes microtubules and lowers the critical concentration for tubulin polymerization. Reversibly binds to polymerized tubulin. Inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells. The checkpoint of mitotic spindle assembly, aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK) are involved in Paclitaxel-induced apoptosis.
Product Specification
Formula: C47H51NO14
MW: 853.9
Purity: ≥98%
Appearance: White solid.
CAS: 33069-62-4
MI: 14: 6982
Source/Host: Isolated from the bark of the Pacific Yew tree (Taxus brevifolia)
Solubility: Soluble in ethanol, DMSO or acetonitrile.
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Store solutions at -20°C for up to 6 months.
Hazard: IRRITANT.
TOXIC.
Handling: Keep cool and dry.
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