BML-TG1914-0100 100 µg 14-3-3 proteins are phosphoserine- and phosphothreonine-binding proteins, and as a family are known to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation state and stability, transcription, metabolism, and malignant transformation. 14-3-3τ/θ (τ in humans, θ in mice) interaction with CDC25c regulates entry into the cell cycle and apoptosis can be prevented following interaction with Bad. 14-3-3 τ/θ (τ in humans, θ in mice) has been shown to be present in testis and 14-3-3τ mRNA is up-regulated in amyotrophic lateral sclerosis spinal cord.
Product Specification
Purity Detail: Purifed.
Formulation: Liquid. In PBS containing 3 mM sodium azide.
Clone: 3B9
Isotype: Mouse IgG
Immunogen: Recombinant full length mouse 14-3-3θ.
Specificity: Recognizes human, mouse, rat and cow 14-3-3τ/θ.
Application: ELISA
Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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