BML-UW0210-0001 1 mg For production of poly-ubiquitin chains via Lys6 only. Lys6-only ubiquitin contains only a single lysine at position 6, with all other lysines mutated to arginine. This mutation renders ubiquitin able to form poly-ubiquitin chains only via Lys6. The ability to form an active thioester at the C-terminus is preserved, allowing Lys6-only ubiquitin to be transferred to the lysines of substrate proteins.
Product Specification
Source/Host: Produced in E. coli.
Application: 1. Production of Lys6-linked poly-ubiquitin chain conjugated proteins.
2. Investigation of the formation and/or function of specific proteins modified by Lys6-linked poly-ubiquitin chains.
3. Study of the production and/or role of poly-ubiquitin chains linked via Lys6 only.
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