BML-AP200-0025 25 mg
BML-AP200-0005 5 mg Active metabolite of sulindac (Prod. No. ALX-430-105). Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.
Product Specification
Alternative Name: Z-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid
Formula: C20H17FO2S
MW: 340.4
Purity: ≥99% (TLC)
Appearance: Yellow-orange solid.
CAS: 32004-67-4
Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (5mg/ml, warm).
Shipping: AMBIENT
Long Term Storage: Ambient
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C.
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