产地：Biomol 
货号：BML-AP309-0020
规格：20 mg
名称：Necrostatin-1
保存温度：-20°C
BML-AP309-0100 100 mg
BML-AP309-0020 20 mg
Necrostatin-1 inhibits necroptosis, a non-apoptotic cell death pathway. Inhibits the loss of mitochondrial membrane potential in TNFα-treated Jurkat cells (EC50=490 nM). Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. It displays a pronounced protective effect in a mouse model of ischemic brain injury and inhibits myocardial cell death. Inhibits RIP1 kinase the key upstream kinase involved in the activation of necroptosis (EC50=180nM).
Product Specification
Alternative Name: Methylthiohydantoin-DL-tryptophan
Formula: C13H13N3OS
MW: 259.3
Purity: ≥98% (TLC)
Appearance: Yellow solid.
CAS: 4311-88-0
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (6mg/ml).
Shipping: AMBIENT
Long Term Storage: Ambient
Use/Stability: Stock solutions are stable for up to 3 months when stored at -20°C.
Handling: Protect from light.
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