BML-EI279-0050 50 mg BML-EI279-0010 10 mg An irreversible inhibitor of cytokine-inducible IκBα phosphorylation (IC50=10 µM). In intact HUVECs it inhibits TNFα-induced phosphorylation and degradation of IκBα without affecting constitutive phosphorylation. Inhibition of IκBα phosphorylation and degradation results in the inactivation of NF-κB and NF-κB-dependent expression of endothelial-leukocyte adhesion molecules, E-selectin, VCAM-1 and ICAM-1. BAY 11-7085 displayed potent anti-inflammatory activity in the rat carrageenan paw edema assay and adjuvant arthritis model. Product Specification Formula: C13H15NO2S MW: 249.3 Purity: ≥99% Appearance: White solid. CAS: 196309-76-9 Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml). Insoluble in water. Long Term Storage: Ambient Handling: Keep under inert gas. Protect from light. 订购电话:021-51870956 在线QQ：470003480 快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧!
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