14-3-3 zeta/delta(YWHAZ)antibody
Cat.#: 5175-1
Rabbit Monoclonal Antibody
Clone ID: EPR6379
Swiss Prot: P63104
Mol Weight: 27kDa
Size: 100ul

Description
14-3-3 zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. 14-3-3 zeta/delta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity (1).

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:50,000 - 200,000

Species Reactivity
Human, Mouse, Rat

Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) SH-SY5Y, (C) Raji, (D) HepG2, (E) C6, (F) Raw264.7, (G) PC-12, and (H) NIH/3T3 cell lysates using anti-14-3-3 zeta/delta RabMAb (cat. #5175-1).

Specificity
A synthetic peptide corresponding to residues near the N-terminus of human 14-3-3 zeta/delta was used as an immunogen.

Storage Condition and Buffer
Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
YWHAZ antibody, 14-3-3-zeta antibody, KCIP-1 antibody, MGC111427 antibody, MGC126532 antibody, MGC138156 antibody, YWHAD antibody, 14-3-3 protein zeta/delta antibody, Protein kinase C inhibitor protein 1 antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.