AK2 Antibody(N-term)
Cat.#: T3054
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P54819
Mol Weight: 26kDa
Size: 100ug

Description
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:100~500
IHC: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human, Mouse

Products Data 

 

The anti-AK2 Pab is used in Western blot to detect AK2 in mouse kidney tissue lysate.
Western blot analysis of anti-AK2 Antibody (N-term) in CEM cell line lysates (35ug/lane). AK2(arrow) was detected using the purified Pab.

Specificity
This AK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~31 amino acids from the N-terminal region of human AK2.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Alternative Names
AK2 antibody, ADK2 antibody, AK 2 antibody, Adenylate kinase 2, mitochondrial antibody, ATP-AMP transphosphorylase 2 antibody

Description References
Noma, T., et al., Biochim. Biophys. Acta 1395(1):34-39 (1998).
Lee, Y., et al., J. Biochem. 123(1):47-54 (1998).
Lee, Y., et al., Biochem. Mol. Biol. Int. 39(4):833-842 (1996).
Bruns, G.A., et al., Biochem. Genet. 15 (5-6), 477-486 (1977).