产品描述
ALDH7A1 antibody
Cat.#: 2022-1
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P49419
Mol Weight: 55kDa
Size: 100ul
Description
Antiquitin (Aldh7a1) is an evolutionarily conserved protein believed to play a role in the regulation of cellular turgor. Based on sequence analysis, this protein is classified as a member of the aldehyde dehydrogenase superfamily (1). Analysis of the amount of mRNA in various rat and human tissues indicates that the largest amounts are found in rat kidney and liver and in cultured human hepatoma cells. Only minimal amounts were detected in human peripheral blood leukocytes, rat lung, or cultured human fibroblasts (2). The plant homolog of ATQ1 is thought to be involved in regulating turgor pressure, a function that also would be essential for cells of the mammalian cochlea. Northern blots of 13 human fetal tissues show antiquitin to be highly expressed in cochlea, ovary, eye, heart, and kidney (3).
Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:250 - 500
IP: 1:40
Species Reactivity
Human, Mouse
Cross reactivity determined by western blot only.
Products Data
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Specificity
A synthetic peptide corresponding to residues near the N-terminus of human Aldh7a1 was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ALDH7A1 antibody, ATQ1 antibody, EPD antibody, FLJ11738 antibody, FLJ92814 antibody, PDE antibody, Alpha-aminoadipic semialdehyde dehydrogenase antibody, Delta1-piperideine-6-carboxylate dehydrogenase antibody
Description References
1. Tang WK, et al. FEBS Lett 516(1-3):183-6, 2002
2. Lee P, et al. Genomics 21(2):371-8, 1994
3. Skvorak AB, et al. Genomics 46(2):191-9, 1997
