氯霉素
Chloramphenicol
别名: D(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, Chloromycetin™
CAS号: 56-75-7
分子量: 323.13
Application
Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.
Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
相关类型 A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
Antibiotics by Application, Antibiotics for Scale-Up Cell Culture, Bioactive Small Molecules, C-CH, Cell Biology, Cell Culture Supplies, Chemical Structure Class, Core Bioreagents, Genetic Marker Selection, Interferes with Protein Synthesis, Life Science Reagents for Cell Culture, Mechanism of Action, Phenicoles, Research Essentials, Scale-Up Cell Culture using Corning Roller Bottles, Spectrum of Activity
Quality Level PREMIUM
assay ≥98% (TLC)
mp 148-150 °C(lit.)
本产品仅用于生命科学研究实验，不作为任何药物及其他用途。