Replaces Prod. #: ALX-270-243 High affinity cannabinoid receptor (CB) agonist (Ki=62.3nM and 3.3nM at the human cloned CB1 and CB2 receptors, respectively). Potent analgesic in a rat model of neuropathic pain. Activates p42 and p44 MAP kinase via a receptor-mediated signaling. Product Specification Alternative Name: (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone . mesylate Formula: C27H26N2O3·CH3SO3H MW: 522.6 Purity: ≥98% Appearance: Yellow solid. CAS: 131543-23-2 Solubility: Soluble in DMSO; insoluble in water. Shipping: AMBIENT Long Term Storage: +4°C Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at 0-4°C. Stock solutions are stable for up to 3 months at -20°C.
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