Epibatidine is an analgesic alkaloid isolated from the skin of the poison frog Epipedobates tricolor. It is the most potent nicotinic acetylcholine receptor agonist known. The natural (+) enantiomer is only 2-fold more potent than the (-) enantiomer with respect to analgesic activity in mice. Both enantiomers bind with high affinity (Ki=0.045 and 0.058 nM respectively) to rat brain membrane nicotinic receptors. Product Specification MW: 208.7 Purity: 99% CAS: 140111-52-0 Shipping: AMBIENT Long Term Storage: -20°C