产地:Bilmol 货号:BML-CA409-0050 规格:50 ug 名称:Xestospongin C CAS: 88903-69-9 代替产品:ALX-350-382 Product Specification Formula: C28H50N2O2 MW: 446.7 Purity: ≥90% Appearance: White to off-white powder Source/Host: Isolated from an Okinawan marine sponge Xestospongia sp. Solubility: Soluble in DMSO or 100% ethanol Shipping: SHIPPED ON BLUE ICE Long Term Storage: -20°C Handling: Packaged under inert gas. Protect from light. Replaces Prod. #: ALX-350-382 Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca2+ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca2+ and K+ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized ells and not in cells with intact plasma membranes. Has vasodilatory properties.