产地:Biomol 货号:BML-CC210-0200 名称:Butyrolactone I 规格:200 ug 可替代产品:ALX-350-250 Cell permeable and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. G1/S and G2/M transitions, in W138 cells, were inhibited, concurrent with inhibition of the phosphorylations of, respectively, retinoblastoma protein and histone H1. It is an important tool for probing the cellular roles of CDKs. Blocks Fas-induced apoptosis. Displays antitumor activity. Product Specification Formula: C24H24O7 MW: 424.5 Purity: ≥99% (TLC) Appearance: White solid. CAS: 87414-49-1 Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO(>10mg/ml). Shipping: AMBIENT Long Term Storage: -20°C Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. Handling: Protect from light.