Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase. It inhibits mitochondrial permeability transition pore opening. At 50 µM it inhibits dexamethasone- apoptosis in thymocytes, preventing the PARP cleavage and DEVDase (caspase-3 like) activity normally produced by these treatments. Product Specification Formula: C28H38O7 * 3NH3 MW: 531.7 Purity: ≥98% Appearance: Lypophilized solid CAS: 11076-19-0 Reconstitution: Reconstitute to 1mg/ml with distilled water Shipping: AMBIENT Long Term Storage: -20°C
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