Phenobarbital is well established as a potent inducer of cytochrome P-450 2B (CYP2B) expression, and work by different groups has shown that AP-1 might play a role in the induction process, and that insulin is able to supress the effect of phenobarbital. Human CYP2B6 appears to be the primary enzyme involved in the N-demethylation of S-mephenytoin and may contribute to the hepatic metabolism of toluene to benzyl alcohol. Product Specification Alternative Name: CYP2B6 Immunogen: Synthetic peptide corresponding to aa 265-276 of human liver CYP2B6. Source/Host: From rabbit. Specificity: Recognizes human wild-type CYP2B6.1 and all known variants of CYP2B6. Application: Immunohistochemistry Western Blot Shipping: SHIPPED ON BLUE ICE Long Term Storage: -20°C
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