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Analog of polyunsaturated fatty acid. Potent inhibitor of long-chain fatty acyl CoA synthetase. Selectively inhibits arachidonoyl-CoA synthetase in intact cells and the nonspecific acyl-CoA synthetase in cell sonicates IC50=3.6-8.7µM. Inhibits neutrophil functions. Blocks β-cell apoptosis induced by fatty acids (lipoapoptosis) and synthesis of triglycerides, diglycerides and cholesterol esters. Potent vasodilator.
Product Specification
Alternative Name: 2,4,7-Undecatrienal nitrosohydrazone, 2E, 4E, 7E-Undecatriene-1-triazene, WS1228A
Concentration: 1mg/ml
Formula: C11H17N3O
MW: 207.3
Purity: ≥90% (TLC)
Appearance: Liquid. In DMSO.
CAS: 76896-80-5
MeltingPoint: 102-104°C
Solubility: Soluble in DMSO (25mg/ml) or methanol (5mg/ml).
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Use/Stability: Stable for up to 1 year after receipt when stored at -20°C.
Handling: Keep under inert gas.
Protect from light.