HerbimycinA

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Antibiotic. Cell permeable tyrosine kinase inhibitor. It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C. It also inhibits HSP90, NF-κB activation and angiogenesis. Increases the sensitivity of certain cancer cells to chemotherapeutic agents. Blocks mitotic activity. Neurotoxic.
Product Specification
Formula: C30H42N2O9
MW: 574.3
Purity: ≥98%
Appearance: Lyophilized solid.
CAS: 70563-58-5
RTECS: LX8930000
Solubility: Soluble in DMSO or 100% ethanol (1mg/ml).
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Handling: Protect from light.
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