HNMPA-(AM)3

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属性:产地:; 品牌:Biomol ;货期:现货

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HNMPA-(AM)3 is a cell-permeable analog of HNMPA. It inhibits insulin receptor tyrosine kinase activity (IC50=100 µM) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50=10 µM). It has no effect on PKA (at concs. up to 1 mM) or PKC (at concs. up to 420 µM). Inhibits both serine and tyrosine autophosphorylation by the human insulin receptor. Does not affect protein kinase C (PKC) or cAMP-dependent protein kinase (PKA).
Product Specification
Formula: C20H23O10P
MW: 454.4
Purity: ≥98% (TLC)
Appearance: Colorless oil
CAS: 120944-03-8
Solubility: Soluble in DMSO (>20mg/ml) or 100% ethanol (>20mg/ml)
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Solutions are stable for up to 3 months whn stored at -20°C. Avoid alkaline medium, pH>8.0
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