KN-93

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Replaces Prod. #: ALX-430-023
KN-93 is a potent, selective and cell-permeable inhibitor of CaM kinase II (IC50=370 nM). Does not significantly inhibit PKA. Causes cell-cycle arrest in NIH 3T3 fibroblasts and HeLa cells. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets of Langerhans. Induces G1 cell cycle arrest and apoptosis in NIH 3T3 cells.
Product Specification
Formula: C26H29ClN2O4S
MW: 501
Purity: ≥95% (TLC)
Appearance: white to off-white solid
CAS: 139298-40-1
Solubility: Soluble in DMSO (25mg/ml)
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 2 years after receipt. Stock solutions are stale for up to 3 months when stored at -20°C.
Hazard: IRRITANT.
Handling: Hygroscopic.
Protect from light.
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