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快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧！ A highly potent and selective inhibitor of Src family tyrosine kinases, IC50=5 nM for p56lck; p59fynT=6 nM; p60src=170 nM. Inhibition of Src family kinases by PP1 has been shown to: prevent a-thrombin-stimulated Akt phosphorylation, delay PAF-mediated STAT3 phosphorylation, block Zn2+-induced Ras activation, block adhesion-dependent tyrosine phosphorylation of p105HEF1 5, and inhibit HLA-DR-induced tyrosine phosphorylation without affecting the activation of ERK1/2.
Product Specification
Formula: C16H19N5
MW: 281.4
Purity: ≥ 98% (TLC)
Appearance: Tan solid.
CAS: 172889-26-8
Solubility: Soluble in DMSO (25mg/ml), slightly soluble in 100% ethanol.
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
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