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Potent inhibitor of CDK1/cyclin B (IC50=400nM). Also inhibits CDK2/cyclin A (IC50=680nM) , CDK5 (IC50=850nM) and with much less effect other kinases. More recently, kenpaullone has been found to be a useful GSK-3β inhibitor (IC50=23nM).
Product Specification
Alternative Name: 9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one
Formula: C16H11BrN2O
MW: 327.2
Purity: ≥98%
Appearance: Tan solid.
CAS: 142273-20-9
Solubility: Soluble in DMSO (>25mg/ml); insoluble in water or ethanol.
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
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