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Replaces Prod. #: ALX-270-125
Phenolic antioxidant found in grapes and wine. Potent activator of human deacetylase SIRT1 (maximum effect at 100-200μM). Increases longevity in yeast. Displays antiproliferative effect on human breast epithelial cells. Displays a variety of pharmacological activities including: estrogen receptor agonist activity, inhibition of ribonucleotide reductase and DNA synthesis, inhibition of eicosanoid synthesis, cell cycle arrest at S/G2 phase and induction of apoptosis. Inhibits PKD in vitro (IC50=200μM) and in vivo (IC50=800μM), but not PKC isoforms.
Protects against 4-hydroxynonenal (4-HNE) induced oxidative stress and apoptosis. Shows cancer chemopreventive activity. Specific inhibitor of cyclooxygenase-1 (COX-1). Inhibits the hydroperoxidase activity of COX-1. 
Product Specification
Alternative Name: trans-3,4’,5-Trihydroxystilbene
Formula: C14H12O3
MW: 228.2
Purity: ≥98% (TLC)
Appearance: White to off-white solid.
CAS: 501-36-0
MI: 14: 8158
Solubility: Soluble in DMSO (65mg/ml), 100% ethanol or dimethyl formamide; slightly soluble in water (0.1mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored at -20°C. Stock solutions are stable for up to 3 months at -20°C.