Lovastatin

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Inhibits cholesterol/isoprenoid biosynthesis by inhibition of HMG-CoA reductase (Ki for acid form is 1nM) and blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Causes cells to arrest early in the G1 phase. Induces apoptosis in cancer cells.
Product Specification
Alternative Name: Mevinolin, 6-α-Methylcompactin
Formula: C24H36O5
MW: 404.6
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 75330-75-5
MI: 14: 5586
Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (>35mg/ml); insoluble in water.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
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