Mevastatin

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属性:产地:; 品牌:Biomol ;货期:现货

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Mevastatin inhibits isoprenoid biosynthesis by inhibition of HMG-CoA reductase (Ki for acid form is 1 nM) and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. It causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.
Product Specification
Alternative Name: Compactin
Formula: C23H34O5
MW: 390.5
Purity: ≥95%
Appearance: White solid.
CAS: 73573-88-3
Solubility: Soluble in DMSO (20mg/ml) or 100% ethanol (25mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
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