产地:Biomol 货号:BML-G237-0005 规格:5 mg 名称:Cerulenin 保存温度:-20°C Antibiotic. Fatty acid synthase (FAS) inhibitor reported to bind in equimolar ratio to β-keto-acyl-ACP synthase (KAS; IC50=1.5µM), thus inhibiting protein acylation at concentrations of 45-134 µM. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes). Product Specification Alternative Name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide Formula: C12H17NO3 MW: 223.3 Purity: ≥98% (TLC) Appearance: White to off-white solid. CAS: 17397-89-6 MI: 14: 2004 RTECS: JR1670000 Solubility: Soluble in DMSO (>10mg/ml) or 100% ethanol (>10mg/ml). Shipping: AMBIENT Long Term Storage: -20°C Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. Hazard: HARMFUL.