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Glucagon-like peptide 2 is a 33- or 34-amino acid peptide located at the C-terminus of, and cleaved from, pro-glucagon by prohormone convertase 3 (PC3). GLP-2 is a potent intestinotropic growth factor, the action of which is transduced by G protein-coupled membrane-bound receptors (GLP2-R) found in the gut. GLP-2Rs are also found in the rodent CNS. The main actions of GLP-2 appear to be crypt cell proliferation, inhibition of enterocyte apoptosis, enhancement of nutrient adsorption and certain reparative effects.
Applications: antiserum adsorption control; standard or tracer for immunoassay.
Product Specification
Alternative Name: GLP 2
MW: 3922.4
Purity: >90%
Appearance: Lyophilized solid.
Sequence: H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg-OH
CAS: 99120-49-7
Solubility: Soluble in dilute acetic acid at 1mg/mL.
Long Term Storage: -20°C