产地：Biomol 
货号：BML-KC155-0005
规格：5 mg
名称：Paxilline
保存温度：-20°C
Paxilline is an indole alkaloid isolated from Penicillium paxilli. It is a selective and reversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (70% block at 10 nM). In neutrophils, Paxilline blockage of BKCa channels decreased the alkalinization of phagocytic vacuoles and inhibited the microbicidal process. Inhibitor of the cerebellar inositol 1,4,5-triphosphate (InsP(3)) receptor. 
Product Specification
Formula: C27H33NO4
MW: 435.6
Purity: ≥97% (HPLC)
Appearance: White solid.
CAS: 57186-25-1
RTECS: DJ2830000
Solubility: Soluble in DMSO (50mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Hazard: TOXIC.
Handling: Protect from light.