货号:BML-N110-0005 产地:Biomol Selective PAR-2 antagonist. Dose dependently inhibits calcium signaling in Lewis lung carcinoma cells stimulated with a soluble peptide PAR-2 agonist or trypsin, but not with a soluble PAR-1 agonist. Does not inhibit platelet aggregation stimulated by thrombin suggesting that it does not inhibit PAR-3 or PAR-4 signaling. Reduces TNF-α and IL-1β production from rheumatoid arthritis synovial primary cell culture and reduces joint swelling in a carageenan/kaolin-injected mouse model. Product Specification Formula: C15H29N3O2 . HCl . H2O MW: 283.3 . 36.5 . 18.0 Purity: ≥98% (TLC) Appearance: White solid. Solubility: Soluble in water (5mg/ml), DMSO (2.5mg/ml) or 100% ethanol (5mg/ml). Shipping: AMBIENT Long Term Storage: -20°C Use/Stability: Store solutions at -20°C for up to 3 months. 订购电话:021-51870956 在线QQ:470003480 快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧!