产地:Biomol
货号:BML-P128-0001
Fluorogenic substrate for several matrix metalloproteinases (MMPs). It is cleaved by MMP-1, MMP-3, MMP-7, MMP-8, MMP-9, MMP-11, MMP-12, MMP-13, and ADAM9/MDC9, but only slightly by MMP-2 and not at all by ADAM17/TACE. Ex/Em= 340nm/440nm, although 365/450 is also appropriate. Highly quenched, with strong fluorescence by Nma at 440nm once cleavage separates it from the aromatic Dnp moiety. Compatible with most fluorometers.
Product Specification
Alternative Name: Matrix metalloproteinase substrate, Dnp-Pro-β-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH2
MW: 1077.2
Purity: ≥98% (HPLC)
Appearance: lyophylized solid
Sequence: Dnp-Pro-ß-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH2 (Dnp=2,4-dinitrophenyl; Nma=N-Me-2-aminobenzoyl)
Solubility: Soluble in DMSO (at least 20mM)
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Handling: Protect from light.
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