产地：Biomol
货号：BML-P132-0500
Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OmniMMPTM Fluorogenic Control peptide (BML-P127).
Product Specification
Alternative Name: ADAM17 substrate
MW: 1638.7
Purity: 96%
Sequence: Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 [Mca=(7-methoxycoumarin-4-yl)acetyl; Dpa=N-3(2,4-dinitrophenyl)-L-a,ß-diaminopropionyl]
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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