产地：Biomol
货号：BML-P320-0001
This sequence, KKHTDDGYMPMSPGVA, is from insulin receptor substrate-1 (IRS-1) inclusive of Tyr608 (mouse) -Tyr612 (human). It contains the insulin receptor tyrosine kinase substrate motif YMXM (Tyr-Met-X-Met). This peptide has been used as a substrate for purified insulin receptor (Km=90 µM) and other tyrosine kinases in phosphocellulose binding assays. The tyrosine phosphorylated version of this peptide binds to phosphatidylinositol 3-kinase (PI 3-kinase) SH2 domain and activates the enzyme.
Product Specification
Alternative Name: Insulin receptor substrate (Tyr608) peptide
MW: 1732.8
Purity: 97%
Appearance: Lyophilized solid.
Sequence: Lys-Lys-His-Thr-Asp-Asp-Gly-Tyr-Met-Pro-Met-Ser-Pro-Gly-Val-Ala
Solubility: Soluble in water.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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