BML-PI130-0050 50 mg BML-PI130-0010 10 mg A potent and selective cell permeable calpain inhibitor. Inhibits oxidative damage-induced apoptosis in PC12 cells and capsaicin-induced apoptosis in dorsal root ganglion neurons. It protects against anoxia in rat optic nerves and reduces neuronal damage in an animal model of global cerebral ischemia(50 mg/kg). In isolated hippocampal pyramidal neurons, it inhibits Ca2+-induced suppression of neurite outgrowth (complete inhibition at 20 µM). Calpain I Ki = 8 nM; Cathepsin B Ki = 24 nM in isolated enzyme assays. IC50 = 0.3 µM in intact cell assay. Product Specification Alternative Name: Z-Val-Phe-CHO Concentration: C22H26N2O4 MW: 382.5 Purity: ≥98% (TLC) Appearance: White solid Sequence: Z-Val-Phe-CHO CAS: 88191-84-8 Solubility: Soluble in DMSO (200mM) Shipping: SHIPPED ON BLUE ICE Long Term Storage: -20°C 订购电话:021-51870956 在线QQ:470003480 快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧!