Catalogue Number | ANT-133 |
Synonyms | LAB7, CD28LG, CD28LG1, CD28LG1, B71. |
Type | Rat Anti Mouse Monoclonal. |
Introduction | The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor. |
Clone | mB7-1. |
Immunogen | Purified mouse LPS-activated B cells. |
Ig Subclass | Rat IgG2a. |
Purification Method | Ion exchange column. |
Protein concentration | 1mg/ml in PBS (after reconstitution). |
Storage Procedures | Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |
Reconstitution | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC. |
Antibody Properties | Blocking and staining antibody. For staining, use 10 µl/106 cells. Titer for blocking T cell activation should be determined by the investigator. |
Available Conjugates | This antibody is only available as purified antibody. |
Usage | Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |