Note: The high-capacity Dionex IonPac AS11-HC column is now recommended for determination of organic acids and inorganic anions in complex sample matrices or uncharacterized samples.
Superior Chromatographic Performance
The Dionex IonPac ICE-AS6 provides improved peak efficiencies and selectivity for carboxylic acids and alcohols. Specifically, it:
Separates weakly ionized acids by differences in pKa, size, and hydrophobicity
Elutes strong acid anions (e.g, chloride and sulfate) into the void so they do not interfere with quantification of organic acids
Achieves difficult separations, including tartrate from citrate, glycolate from lactate and formate, lactate from malate, and formate from succinate
Is compatible with any typical strong acid eluent and a wide variety of detectors, including amperometry, photometry, and refractive index
Uses HPLC solvents to control hydrophobic retention of higher- molecular-weight acids or for effective column cleanup
Increased Sensitivity with Suppressed Conductivity Detection
Dionex IonPac ICE-AS1 column should be used with the Dionex Anion MicroMembrane™ Ion-Exclusion Suppressor (AMMS™ ICE 300), which is a low-void volume, high-capacity eluent suppressor.
The AMMS™ ICE 300 suppressor reduces the background conductivity of the eluent, while increasing the conductivity of the analytes.