产品编号 C7505 | CAS号 56-88-2 | SIGMA

L-Cystathionine

≥98% (TLC)

安全技术说明书

别名: (R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine

• 经验分子式（希尔表示法） C₇H₁₄N₂O₄S

   

• 分子量 222.26

   

•  Beilstein Registry Number 2505200

•  EINECS 编号 200-295-8

   

•  MDL number MFCD00036685

   

•  PubChem Substance ID 24892965

• POPULAR DOCUMENTS:  SPECIFICATION SHEET (PDF)

  产品描述

  包装

  10 mg in glass bottle

  50, 250 mg in poly bottle

  Application

  L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.^[5]

  Biochem/physiol Actions

  L-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine.^[1][2] It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s).^[3] L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders.^[4] In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.^[2]

  Other Notes

  Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7505.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

   

  性质

  Related Categories	Amino Acid, 代谢组学, 代谢通路, 代谢通路图中的代谢产物和辅酶分子, 细胞生物学 更多...
  InChI Key	ILRYLPWNYFXEMH-WHFBIAKZSA-N
  assay	≥98% (TLC)
  storage temp.	−20°C

  美国sigma-aldrich是全球最大的化工试剂生产商，Sigma-Aldrich 是一个生物/ 化学试剂领先的高科技企业。我们的生化试剂，有机化学试剂和试剂盒广泛应用于基因组学研究，生物科技，药物研发，疾病诊断和化工生产上。我们的客户遍及生命科学公司，大学，研究机构，医院以及工业部门。其客户遍及160个国家地区，在35个国家有分支机构，雇员超过6,800人。 
  【Sigma-Aldrich 中国代理商：联硕生物科技有限公司】

  

   Sigma-Aldrich is a leading Life Science and High Technology company. Our chemical and biochemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical, diagnostic and other high technology manufacturing.