产品描述
| 溶解性 | Soluble in water (<1 mg/ml) at 25 °C, DMSO (13 mg/ml) at 25 °C, and ethanol (<1 mg/ml) at 25 °C. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A selective Chk1 inhibitor. |
| 产品介绍 | Y2603618是一种选择性Chk1抑制剂，具有潜在的抗肿瘤活性。Phase 2。 |
| 备注 | LY2603618 is a selective Chk1 inhibitor with potential anti-tumor activity. |
| 生化机理 | LY2603618 (IC-83) is a very selective checkpoint kinase 1 (Chk1) inhibitor with the potential for antitumor effects. Chk1 is an ATP-dependent serine-threonine kinase that is very important to the checkpoint monitoring system of DNA replication. |
| 别名 | N-[5-溴-4-甲基-2-[(2S)-2-吗啉甲氧基]苯基]-N'-(5-甲基-2-吡嗪基)脲;IC-83; LY 2603618; LY-2603618;N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)urea;(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea |
