产品描述
| 溶解性 | Soluble in DMSO (113 mg/mL at 25 °C), water (3 mg/mL at 25 °C), and ethanol (15 mg/mL at 25 °C). |
| 存贮条件 | 储存温度-20°C |
| 应用 | An inhibitor of JAK2. |
| 产品介绍 | NVP-BSK805 2HCl是一种有效的，选择性的，ATP竞争性的JAK2抑制剂，IC50为0.5 nM，比作用于JAK1， JAK3和TYK2选择性高20倍以上。 |
| 备注 | NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM,>20-fold selectivity towards JAK1, JAK3 and TYK2. |
| 生化机理 | NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM. |
| 别名 | 8-[3,5-二氟-4-(4-吗啉基甲基)苯基]-2-[1-(4-哌啶基)-1H-吡唑-4-基]喹喔啉;BSK805 dihydrochloride; NVP-BSK 805 dihydrochloride;8-[3,5-Difluoro-4-(4-morpholinylmethyl)phenyl]-2-[1-(4-piperidinyl)-1H-pyrazol-4-yl]quinoxaline |
