产品描述
| 熔点 | 260-262 °C |
| 溶解性 | Soluble in DMSO (100 mg/mL), and methanol. Insoluble in ethanol, and water |
| 存贮条件 | 储存温度-20°C |
| 应用 | A novel and potent inhibitor of B-RAFV600E with IC50 of 31 nM. |
| 产品介绍 | Vemurafenib (PLX4032, RG7204)是一种新型有效的B-Raf V600E抑制剂，IC50为31 nM。 |
| 备注 | Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM. |
| 生化机理 | Vemurafenib is a novel and potent inhibitor of B-RAFV600E with IC50 of 31 nM. Has been shown to kill melanoma cells in vitro. |
| 别名 | 维罗非尼;PLX-4032; RG7204; R7204; RO5185426; PLX4032;N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide |
