熔点 | 274°C(dec.)(lit.) |
溶解性 | Soluble in DMSO (29 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
存贮条件 | 储存温度2-8℃ |
应用 | A potent inhibitor of dihydropyrimidine dehydrogenase (DPD). |
产品介绍 | Gimeracil是一种二氢脱氢酶的抑制剂,在双链断裂修复中,抑制早期同源重组。 |
备注 | Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair. |
生化机理 | Gimeracil is an antitumor agent and a potent inhibitor of dihydropyrimidine dehydrogenase (DPD). |
别名 | 吉美拉西;吉美嘧啶;吉莫斯特;4-羟基-5-氯-2-(1H)吡啶酮;Gimestat;CDHP;5-Chloro-2,4-dihydroxypyridine;5-Chloro-4-hydroxy-2(1H)-pyridinone;5-Chloro-2,4-pyridinediol |