产品描述
| 溶解性 |
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| 存贮条件 | 储存温度 2-8°C |
| 应用 | A potent and selective MAO-B inhibitor. |
| 产品介绍 | Safinamide Mesylate是Safinamide的甲磺酸盐，是一种选择性的且可逆的MAO-B抑制剂，IC50为98 nM，比作用于MAO-A选择性高5918倍。 |
| 备注 | Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3. |
| 生化机理 | Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM. |
| 别名 | 沙芬酰胺甲磺酸盐;Safinamide mesylate salt;(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide; FCE-26743; PNU-151774E; NW-1015 |
