溶解性 |
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存贮条件 | 储存温度2-8℃ |
应用 | A selective irreversible MAO-B inhibitor |
产品介绍 | Rasagiline Mesylate是一种新型MAO-B抑制剂,用于治疗突发性帕金森病。 |
备注 | Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease. |
生化机理 |
Rasagiline Mesylate is an antiparkinsonian and a selective irreversible MAO-B inhibitor. Rasagiline mesylate is an effective therapeutic option in early stages of Parkinson′s disease. It improves the motor fluctuations in levodopa-treated patients and may be a useful adjunct to such patients. It has neuroprotective effects and increases the survival of dopaminergic neurons. Rasagiline mesylate is an irreversible inhibitor of monoamine oxidase selective for MAO type B over type A by a factor of fourteen. It has anti-apoptotic and neuroprotectant activity and has been used as a treatment for Parkinson′s disease. |
别名 | 甲磺酸雷沙吉兰; (R)-N-2-丙炔基-1-氢化茚胺甲磺酸盐;TVP-1012;(R)-N-2-Propynyl-1-indanamine methanesulfonate;(1R)-2,3-Dihydro-N-2-propynl-1H-inden-1-amine methanesulfonate;N-Propargyl-1(R)-aminoindan methanesulfonate |