熔点 | 182°C |
敏感性 | 对湿度敏感 |
溶解性 | Soluble in DMSO (47 mg/mL at 25 °C), chloroform (<1 mg/mL at 23 °C), water (<1 mg/mL at 25 °C), ethanol (<1 mg/mL at 25 °C), and methanol (6 mg/mL at 23 °C). |
存贮条件 | 储存温度-20°C |
应用 | A potent anti-retroviral agent that acts by competing with natural dATP. |
产品介绍 | Didanosine是一种逆转录酶抑制剂,IC50为0.49 μM。 |
备注 | Didanosine(Videx, Videx EC) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. |
生化机理 | 2′,3′-Dideoxyinosine is a potent anti-retroviral agent. 2′,3′-Dideoxyinosine is most effective in combination therapy for the treatment of HIV and related lymphoma. |
别名 | 地丹诺辛;2',3'-双脱氧肌苷;2',3'-双脱氧肌甙;2',3'-二脱氧肌苷;2',3'-二脱氧肌苷 ;地达诺辛;ddI;ddIno;ddI;ddIno;2',3'-Dideoxyinosine;9-(2,3-Dideoxy-β-D-ribofuranosyl)hypoxanthine;9-(2,3-Dideoxy-β-D-ribofuranosyl)-6-oxopurine |